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Damiano Rizzoni Selected Research

MDL 100240

4/2004Bradykinin and matrix metalloproteinases are involved the structural alterations of rat small resistance arteries with inhibition of ACE and NEP.
7/2002Dual ACE and NEP inhibitor MDL-100,240 prevents and regresses severe angiotensin II-dependent hypertension partially through bradykinin type 2 receptor.
2/2002Comparative effects of the dual ACE-NEP inhibitor MDL-100,240 and ramipril on hypertension and cardiovascular disease in endogenous angiotensin II-dependent hypertension.

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Damiano Rizzoni Research Topics

Disease

38Hypertension (High Blood Pressure)
01/2022 - 02/2002
15Essential Hypertension
01/2018 - 01/2002
9Hyperaldosteronism (Conn Syndrome)
01/2010 - 07/2006
8Type 2 Diabetes Mellitus (MODY)
12/2018 - 03/2004
7Vascular Remodeling
01/2022 - 04/2002
7Inflammation (Inflammations)
01/2022 - 06/2014
7Adenoma (Adenomas)
01/2010 - 08/2006
5Pneumonia (Pneumonitis)
07/2021 - 07/2020
5Neoplasms (Cancer)
01/2021 - 06/2008
4Body Weight (Weight, Body)
01/2005 - 02/2002
3Respiratory Insufficiency (Respiratory Failure)
12/2020 - 07/2020
3COVID-19
12/2020 - 07/2020
3Microvascular Rarefaction
06/2017 - 08/2008
3Cardiovascular Diseases (Cardiovascular Disease)
08/2015 - 02/2002
3Hypertrophy
04/2004 - 02/2002
2Heart Failure
06/2021 - 01/2021
2Chronic Obstructive Pulmonary Disease (COPD)
06/2021 - 12/2020
2Heart Diseases (Heart Disease)
12/2020 - 01/2019
2Diabetes Mellitus
12/2018 - 01/2018
2Fibrosis (Cirrhosis)
01/2018 - 06/2013
2Chronic Renal Insufficiency
01/2018 - 01/2018
2Hypoxia (Hypoxemia)
05/2015 - 06/2014
2Obesity
06/2014 - 06/2013
2Weight Loss (Weight Reduction)
06/2013 - 07/2011
2Renovascular Hypertension (Goldblatt Syndrome)
12/2009 - 03/2004
2Cardiomegaly (Heart Hypertrophy)
12/2009 - 04/2002
2Hyperplasia
04/2004 - 12/2003
1Pulmonary Fibrosis (Fibrosing Alveolitis)
07/2021
1Cough
06/2021
1Platypnea Orthodeoxia Syndrome
01/2021
1Infections
08/2020
1Lymphopenia (Lymphocytopenia)
07/2020

Drug/Important Bio-Agent (IBA)

11Antihypertensive Agents (Antihypertensives)IBA
12/2016 - 05/2003
9AldosteroneIBA
01/2010 - 07/2006
8Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
01/2021 - 04/2004
7EnalaprilFDA LinkGeneric
10/2017 - 02/2005
5Retinaldehyde (Retinal)IBA
01/2021 - 02/2014
5Angiotensin Receptor AntagonistsIBA
01/2021 - 02/2005
5Endothelins (Endothelin)IBA
01/2018 - 01/2005
4lercanidipineIBA
10/2017 - 03/2014
4Norepinephrine (Noradrenaline)FDA LinkGeneric
05/2015 - 04/2002
4Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
12/2014 - 07/2002
4Ramipril (Altace)FDA LinkGeneric
10/2014 - 02/2002
4CollagenIBA
06/2013 - 10/2003
3Monoclonal AntibodiesIBA
01/2021 - 07/2020
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021 - 06/2017
3Endothelin-1 (Endothelin 1)IBA
01/2018 - 01/2002
3Hydrochlorothiazide (Esidrix)FDA LinkGeneric
10/2017 - 04/2011
3Angiotensin IIIBA
01/2017 - 02/2002
3Captopril (Capoten)FDA LinkGeneric
05/2015 - 12/2006
3Insulin (Novolin)FDA Link
12/2014 - 01/2008
3ReninIBA
01/2010 - 12/2006
3MDL 100240IBA
04/2004 - 02/2002
2CytokinesIBA
01/2022 - 12/2014
2Hydroxychloroquine (Plaquenil)FDA LinkGeneric
12/2020 - 08/2020
2LopinavirFDA Link
12/2020 - 08/2020
2Ritonavir (Norvir)FDA Link
12/2020 - 08/2020
2tocilizumab (atlizumab)FDA Link
08/2020 - 07/2020
2MelatoninIBA
01/2017 - 06/2014
2Calcium Channel Blockers (Blockers, Calcium Channel)IBA
12/2016 - 12/2014
21,4-dihydropyridine (dihydropyridine)IBA
12/2016 - 12/2014
2AntioxidantsIBA
12/2016 - 06/2014
2Pharmaceutical PreparationsIBA
09/2016 - 07/2005
2Biomarkers (Surrogate Marker)IBA
08/2015 - 09/2010
2Telmisartan (Micardis)FDA Link
05/2015 - 12/2014
2Nifedipine (Adalat)FDA LinkGeneric
12/2014 - 07/2005
2mepirodipine (barnidipine)IBA
08/2011 - 04/2011
2Vasodilator Agents (Vasodilators)IBA
04/2010 - 03/2003
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2009 - 03/2004
2NebivololFDA Link
01/2009 - 05/2003
2SodiumIBA
07/2008 - 08/2007
2candesartanIBA
04/2005 - 02/2005
2candesartan cilexetil (Amias)FDA Link
04/2005 - 02/2005
2Proteins (Proteins, Gene)FDA Link
02/2005 - 04/2004
2Neprilysin (Neutral Endopeptidase)IBA
04/2004 - 07/2002
2Phenylephrine (Neo-Synephrine)FDA LinkGeneric
04/2002 - 02/2002
1Indicators and Reagents (Reagents)IBA
07/2021
1Carbon MonoxideIBA
07/2021
1Oxygen (Dioxygen)IBA
01/2021
1Tyrosine Kinase InhibitorsIBA
01/2021
1AnticoagulantsIBA
12/2020
1Enoxaparin (Lovenox)FDA LinkGeneric
12/2020
1Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
08/2020
1Fibrinogen (Factor I)FDA Link
07/2020
1C-Reactive ProteinIBA
07/2020
1Ferritins (Ferritin)IBA
07/2020
1Interleukin-6 (Interleukin 6)IBA
07/2020
1Vitamin DFDA LinkGeneric
01/2019
1Glucagon-Like Peptides (Enteroglucagon)IBA
12/2018
1Glucagon-Like Peptide-1 Receptor AgonistsIBA
12/2018
1Exenatide (Byetta)FDA Link
12/2018
1LiraglutideFDA Link
12/2018
1IncretinsIBA
12/2018
1elastin microfibril interface located protein (emilin)IBA
01/2018

Therapy/Procedure

11Therapeutics
01/2022 - 04/2005
3Adrenalectomy
06/2008 - 12/2006
2Aftercare (After-Treatment)
06/2017 - 09/2014
2Abdominoplasty
06/2013 - 07/2011
1Polypharmacy
06/2021
1Intravenous Administration
07/2020